Analysis of Multiple Vitamins Serum Levels and Disease-Related Factors in Children with Acute Leukemia

Table 5

Analysis of factors influencing different risk degrees in children with acute leukemia.

Indicators		HR group (n = 44)	IR group (n = 53)	SR group (n = 8)	F/X^2
Age		8.18 ± 10.83	8.98 ± 16.57	5.25 ± 2.92	0.261	0.771
BMI		16.85 ± 2.78	16.58 ± 2.88	14.43 ± 2.5	0.883	0.417
Gender	Male	22 (50)	33 (62.3)	4 (50.0)	1.604	0.448
	Female	22 (50)	20 (37.7)	4 (50.0)
Diagnostic results	ALL	35 (79.5)	40 (75.5)	7 (87.5)	0.681	0.711
	AML	9 (20.5)	13 (24.5)	1 (12.5)
Immunophenotype	AML	8 (18.2)	13 (24.5)	1 (12.5)	1.084	0.897
	B	32 (72.7)	36 (67.9)	6 (75.0)
	T	4 (9.1)	4 (7.5)	1 (12.5)
Liver function	Abnormal	10 (22.7)	16 (30.8)	1 (12.5)	2.119	0.347
	Normal	34 (77.3)	36 (69.2)	7 (87.5)
Renal function	Abnormal	4 (9.1)	11 (20.8)	4 (50.0)	9.869	0.007
	Normal	40 (90.9)	42 (79.2)	4 (50.0)
Icterus	Yes	5 (11.4)	8 (15.1)	0	8.496	0.014
	No	39 (88.6)	45 (84.9)	8 (100.0)
Biochemical indicator	Alanine aminotransferase (ALT, mmol/L)	48.11 ± 106.33	31.58 ± 34.05	47.49 ± 36.33	0.641	0.529
	Aspartate aminotransferase (AST, mmol/L)	41.51 ± 50.47	29.78 ± 23.77	39.57 ± 17.33	1.230	0.297
	Lactate dehydrogenase (LD, U/L)	534.66 ± 1281.05	363.04 ± 728.54	303.86 ± 181.69	0.426	0.654
	Hydroxybutyric dehydrogenase (HBDH, U/L)	386.91 ± 841.45	262.06 ± 491.06	239.14 ± 161.26	0.487	0.616
Serological indicators	White blood cell count (WBC, 10^9/L)	6.99 ± 11.62	12.37 ± 23.50	5.83 ± 4.62	1.203	0.304
	Neutrophils (N, 10^9/L)	3.33 ± 5.50	2.80 ± 4.29	2.72 ± 1.66	0.168	0.846
	Hemoglobin (Hb, g/L)	87.89 ± 18.32	92.45 ± 22.68	97.88 ± 28.54	0.997	0.373
	Platelet count (PLT)	125.39 ± 87.45	189.85 ± 132.01	170.63 ± 92.35	3.964	0.022
(PLT, 10^9/L)	Lymphocyte (L, 10^9/L)	2.76 ± 6.16	6.18 ± 14.67	2.63 ± 3.98	1.224	0.298
	C-reactive protein (CRP, mg/L)	9.63 ± 25.49	9.15 ± 19.36	9.21 ± 14.44	0.006	0.994
	Activated partial thromboplastin time (APTT, s)	30.73 ± 7.70	30.61 ± 5.76	28.36 ± 2.57	0.411	0.664
	Troponin (Tn)	6.79 ± 8.58	5.68 ± 8.62	6.28 ± 11.67	0.192	0.826
Vitamin level	Vitamin A (VA, μmol/L)	0.71 ± 0.18	0.76 ± 0.24	0.71 ± .24	0.944	0.392
	Vitamin B1 (VB1, nmol/L)	98.32 ± 13.29	99.91 ± 12.16	101.67 ± 10.33	0.336	0.715
	Vitamin B2 (VB2, μg/L)	5.42 ± 1.33	5.78 ± 2.25	5.50 ± 1.37	0.466	0.629
	Vitamin B6 (VB6, nmol/L)	34.77 ± 17.05	32.86 ± 13.23	36.43 ± 15.96	0.309	0.735
	Vitamin B9 (VB9, nmol/L)	20.49 ± 6.73	19.54 ± 5.04	18.14 ± 4.94	0.688	0.505
	Vitamin B12 (VB12, pg/mL)	484.54 ± 91.76	474.32 ± 90.16	446.55 ± 76.09	0.635	0.532
	Vitamin C (VC, μmol/L)	38.69 ± 5.26	39.22 ± 6.10	37.51 ± 3.45	0.358	0.700
	Vitamin D (VD, nmol/L)	40.85 ± 15.11	44.04 ± 21.09	36.56 ± .02	0.785	0.459
	Vitamin E (VE, μg/mL)	10.77 ± 0.83	10.62 ± 0.68	10.77 ± 0.87	0.520	0.596

Data were mean ± SD or n (%). Missing = 2. . AML, acute myeloid leukemia; BMI, body mass index; HR, high risk; IR, intermediate risk; SR, slight risk.