[Retracted] Differential Prognostic Analysis of Higher and Lower PEEP in ARDS Patients: Systematic Review and Meta-Analysis

Table 1

Characteristics of all randomized control trials comparing the effect of higher PEEP and lower PEEP on mortality (1966–2021).

Study name	No. of participants (high PEEP)	No. of participants (low PEEP)	Higher PEEP	Lower PEEP	Outcome of interest
Amato et al. [12]	29	24	Lower inflection point + 2 cm H2O	FiO2-PEEP	①②③
Ranieri et al. [13]	18	19	Lower inflection point + 2 cm H2O	FiO2-PEEP	②
Brower et al. [14]	276	273	FiO2-PEEP (ARDSnet)	FiO2-PEEP	①
Villar et al. [15]	50	45	Lower inflection point + 2 cm H2O	FiO2-PEEP	①③
Meade et al. [16]	475	508	FiO2-PEEP	FiO2-PEEP	①②③
Mercat et al. [17]	385	382	Pplat	FiO2-PEEP	①②
Talmor et al. [18]	30	31	Transpulmonary pressure	FiO2-PEEP	②
Huh et al. [19]	30	27	Saturation decrease more	FiO2-PEEP	②③
Hodgson et al. [20]	10	10	PFiO2-PEEP	FiO2-PEEP	①
Kacmarek et al. [21]	99	101	PEEP + 35–45 cm H2O	FiO2-PEEP	①②③
Cavalcanti et al. [22]	501	509	PEEP + 2 cm H2O	FiO2-PEEP	① ②③

①: hospital mortality; ②: 28-day mortality; ③: ICU mortality.