Research Article
[Retracted] Meta-Analysis of the Effectiveness and Safety of Glucocorticoid for the Treatment of IgA Kidney Disease
Table 1
Overall efficacy of hormone in the treatment of IgA nephropathy proteinuria.
| Glucocorticoid group | Control group | Std. mean difference | Study or subgroup | Mean | SD | Total | Mean | SD | Total | Weight | IV, fixed, 95% CI |
| Kobayashi et al., 1996 | 0.8 | 0.5 | 20 | 1.5 | 1.3 | 26 | 8.6% | −0.67 [−1.27,−0.07] | Shoji et al., 2000 | 0.29 | 0.23 | 11 | 0.71 | 0.39 | 8 | 2.9% | −1.31 [−2.33,−0.29] | Locatelli et al., 2001 | 0.67 | 0.5 | 43 | 1.48 | 1.87 | 43 | 16.5% | −0.59 [−1.02,−0.15] | Uzu et al., 2003 | −1.26 | 0.56 | 23 | −0.86 | 0.45 | 22 | 8.4% | −0.77 [−1.38,−0.16] | Moriyama et al., 2004 | 1.02 | 0.98 | 20 | 1.28 | 2.19 | 40 | 10.7% | −0.14 [−0.67, 0.40] | Hogg et al., 2006 | −1.26 | 0.56 | 34 | −0.86 | 0.45 | 31 | 12.1% | −0.77 [−1.28, −0.27] | Koike et al., 2008 | 0.31 | 0.51 | 24 | 0.68 | 0.69 | 24 | 9.2% | −0.60 [−1.18, −0.02] | Lv et al. 2009 | −2.5 | 0.9 | 33 | −2 | 0.8 | 30 | 12.1% | −0.58 [−1.08, −0.07] | Manno et al., 2009 | 1.2 | 2.5 | 48 | 1.4 | 2.3 | 49 | 19.5% | −0.08 [−0.48, 0.32] | Total (95% CI) | | | 256 | | | 273 | 100.0% | −0.51 [−0.68, −0.33] |
|
|
Heterogeneity: Chi-squared = 10.93, df = 8 ( P = 0.21); F = 27%; test for overall effect: Z = 5.65 ( <0.00001). |