Pharmacological Study on Total Glycosides of Xiebai Protecting against Depression Model

Table 1

Effect of total glucosides of Xiebai on body weight of chronic depression model rats ( ± s).

Group	Number of animals	Dose/mg·kg^−1	1 d	7 d	14 d	21 d
Blank group	10	—	198.1 ± 7.3	250.1 ± 16.8	281.6 ± 9.8	300.7 ± 8.7
Model group	10	—	195.8 ± 8.0	248.4 ± 15.1	259.7 ± 16.9	269.6 ± 17.0
Fluoxetine hydrochloride group	10	6.6	197.7 ± 8.9	250.1 ± 13.5	280.0 ± 16.6	290.5 ± 17.3
High-dose Xiebai total glycosides group	10	200	193.5 ± 6.9	239.8 ± 12.3	278.6 ± 12.8	292.5 ± 12.8
Medium-dose Xiebai total glycosides group	10	100	196.6 ± 8.6	245.1 ± 14.4	272.8 ± 11.3	283.7 ± 11.4
Low-dose Xiebai total glycosides group	10	50	192.5 ± 7.4	248.6 ± 17.9	263.7 ± 11.3	281.0 ± 12.1

Note. Compared with the model group,  < 0.05 and  < 0.01.