Research Article

Pharmacological Study on Total Glycosides of Xiebai Protecting against Depression Model

Table 2

Effect of total glucosides of Xiebai on syrup consumption and swimming time in rats with chronic stress depression ( ± s).

GroupNumber of animalsDose (mg·kg−1)Sugar consumption (ml)Static time (s)

Blank group1076.9 ± 8.562.4 ± 12.2
Model group1053.6 ± 7.8117.1 ± 19.9
Fluoxetine hydrochloride group106.667.2 ± 7.682.7 ± 12.1
High-dose Xiebai total glycosides group1020066.9 ± 7.389.7 ± 16.7
Medium-dose Xiebai total glycosides group1010062.0 ± 4.9103.0 ± 16.7
Low-dose Xiebai total glycosides group105059.9 ± 5.1107.6 ± 13.5

Note. Compared with the model group,  < 0.05 and  < 0.01.