Research Article
Pharmacological Study on Total Glycosides of Xiebai Protecting against Depression Model
Table 2
Effect of total glucosides of Xiebai on syrup consumption and swimming time in rats with chronic stress depression (
±
s).
| Group | Number of animals | Dose (mg·kg−1) | Sugar consumption (ml) | Static time (s) |
| Blank group | 10 | — | 76.9 ± 8.5 | 62.4 ± 12.2 | Model group | 10 | — | 53.6 ± 7.8 | 117.1 ± 19.9 | Fluoxetine hydrochloride group | 10 | 6.6 | 67.2 ± 7.6 | 82.7 ± 12.1 | High-dose Xiebai total glycosides group | 10 | 200 | 66.9 ± 7.3 | 89.7 ± 16.7 | Medium-dose Xiebai total glycosides group | 10 | 100 | 62.0 ± 4.9 | 103.0 ± 16.7 | Low-dose Xiebai total glycosides group | 10 | 50 | 59.9 ± 5.1 | 107.6 ± 13.5 |
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Note. Compared with the model group, < 0.05 and < 0.01. |