Pharmacological Study on Total Glycosides of Xiebai Protecting against Depression Model

Table 3

Effect of total glucosides of Xiebai on 5-HT content in chronic stress depression rats ( ± s).

Group	Number of animals	Dose (mg·kg^−1)	5-HT (ng·ml^−1)	DA (pg·ml^−1)	NE (ng·ml^−1)
Blank group	10	—	81.12 ± 5.96	251.24 ± 17.26	85.62 ± 4.91
Model group	10	—	58.17 ± 8.62	183.71 ± 17.51	54.42 ± 10.12
Fluoxetine hydrochloride group	10	6.6	73.17 ± 8.21	220.32 ± 25.29	75.20 ± 12.67
High-dose Xiebai total glycosides group	10	200	72.52 ± 11.77	210.53 ± 24.42	69.93 ± 14.17
Medium-dose Xiebai total glycosides group	10	100	72.76 ± 12.28	214.50 ± 15.74	68.32 ± 10.18
Low-dose Xiebai total glycosides group	10	50	67.97 ± 7.33	203.63 ± 19.84	66.22 ± 10.92

Note. Compared with the model group,  < 0.05 and  < 0.01.