Pharmacological Study on Total Glycosides of Xiebai Protecting against Depression Model

Table 4

Effect of total glucosides of Xiebai on ACTH content in chronic stress depression rats ( ± s).

Group	Number of animals	Dose (mg·kg^−1)	ACTH (pg·ml^−1)	CORT (ng·ml^−1)
Blank group	10	—	26.68 ± 4.26	126.19 ± 32.73
Model group	10	—	34.70 ± 3.46	191.58 ± 27.65
Fluoxetine hydrochloride group	10	6.6	25.99 ± 5.70	147.34 ± 31.75
High-dose Xiebai total glycosides group	10	200	30.75 ± 2.68	141.30 ± 28.32
Medium-dose Xiebai total glycosides group	10	100	31.59 ± 2.17	156.11 ± 29.79
Low-dose Xiebai total glycosides group	10	50	35.05 ± 3.72	167.62 ± 31.96

Note. Compared with the model group,  < 0.05 and  < 0.01.