Research Article
Pharmacological Study on Total Glycosides of Xiebai Protecting against Depression Model
Table 9
Effect of total glucosides of Xiebai on pathological changes of the adrenal gland in rats with chronic depression.
| Group | Number of animals | Dose (mg·kg−1) | Adrenal cortex thickness |
| Blank group | 10 | — | 625.7 ± 71.1 | Model group | 10 | — | 942.9 ± 148.1 | Fluoxetine hydrochloride group | 10 | 6.6 | 728.5 ± 134.2 | High-dose Xiebai total glycosides group | 10 | 200 | 726.9 ± 92.3 | Medium-dose Xiebai total glycosides group | 10 | 100 | 800.7 ± 153.3 | Low-dose Xiebai total glycosides group | 10 | 50 | 847.5 ± 123.5 |
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Note. Compared with the model group, < 0.05 and < 0.01. |