Research Article

[Retracted] The Effects of Febuxostat on Urine NGAL and Urine KIM-1 in Patients with Hyperuricemia

Table 3

Self-comparison of the two groups before and after treatment.

TimeBUN (mmol/L)CR (μmol/L)eGFR (ml/min/1.73 m2)UA (μmol/L)Urine microalbumin/CR (mg/g)Urine NGAL/CR (μg/g)Urine KIM-1/CR (μg/g)

Febuxostat (n = 25)Baseline5.9 ± 1.980.7 ± 19.699 ± 14555 ± 8150 ± 1512.1 ± 2.42.4 ± 0.5
3 months5.7 ± 2.077.6 ± 24.5103 ± 17319 ± 9824 ± 86.7 ± 2.51.2 ± 0.3
value0.7190.6240.368<0.001<0.001<0.001<0.001
Control (n = 20)Baseline6.1 ± 1.978.1 ± 24.7102 ± 13570 ± 8248 ± 1813.8 ± 4.12.6 ± 0.6
3 months6.0 ± 2.178.0 ± 26.3100 ± 15568 ± 8945 ± 1714.5 ± 4.22.8 ± 0.7
value0.9450.9900.6550.9420.5910.5970.338