Research Article
[Retracted] The Effects of Febuxostat on Urine NGAL and Urine KIM-1 in Patients with Hyperuricemia
Table 3
Self-comparison of the two groups before and after treatment.
| | Time | BUN (mmol/L) | CR (μmol/L) | eGFR (ml/min/1.73 m2) | UA (μmol/L) | Urine microalbumin/CR (mg/g) | Urine NGAL/CR (μg/g) | Urine KIM-1/CR (μg/g) |
| Febuxostat (n = 25) | Baseline | 5.9 ± 1.9 | 80.7 ± 19.6 | 99 ± 14 | 555 ± 81 | 50 ± 15 | 12.1 ± 2.4 | 2.4 ± 0.5 | 3 months | 5.7 ± 2.0 | 77.6 ± 24.5 | 103 ± 17 | 319 ± 98 | 24 ± 8 | 6.7 ± 2.5 | 1.2 ± 0.3 | value | 0.719 | 0.624 | 0.368 | <0.001 | <0.001 | <0.001 | <0.001 | Control (n = 20) | Baseline | 6.1 ± 1.9 | 78.1 ± 24.7 | 102 ± 13 | 570 ± 82 | 48 ± 18 | 13.8 ± 4.1 | 2.6 ± 0.6 | 3 months | 6.0 ± 2.1 | 78.0 ± 26.3 | 100 ± 15 | 568 ± 89 | 45 ± 17 | 14.5 ± 4.2 | 2.8 ± 0.7 | value | 0.945 | 0.990 | 0.655 | 0.942 | 0.591 | 0.597 | 0.338 |
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