Research Article

A Nomogram for Predicting Cardiovascular Diseases in Chronic Obstructive Pulmonary Disease Patients

Table 6

Subgroup analysis of the predictive ability of the prediction model.

SubgroupCharacteristicTesting set (95%CI)

COPD diagnosed by spirometry
AUC0.69 (0.53–0.85)
Accuracy0.83 (0.75–0.88)
Sensitivity0.38 (0.14–0.61)
Specificity0.88 (0.82–0.93)
NPV0.92 (0.87–0.97)
PPV0.27 (0.09–0.46)

COPD diagnosed from the questionnaire
AUC0.72 (0.64–0.80)
Accuracy0.63 (0.55–0.71)
Sensitivity0.70 (0.60–0.81)
Specificity0.61 (0.51–0.72)
NPV0.70 (0.60–0.81)
PPV0.57 (0.45–0.68)

Smoking (yes)
AUC0.79 (0.73–0.85)
Accuracy0.73 (0.67–0.79)
Sensitivity0.65 (0.54–0.76)
Specificity0.76 (0.70–0.83)
NPV0.84 (0.78–0.90)
PPV0.54 (0.44–0.64)

Smoking (no)
AUC0.64 (0.45–0.83)
Accuracy0.72 (0.59–0.83)
Sensitivity0.22 (0.01–0.49)
Specificity0.82 (0.71–0.92)
NPV0.85 (0.75–0.95)
PPV0.18 (0.01–0.41)

AUC: the area under the curve, NPV: negative predictive value, PPV: positive predictive value.