The Therapeutic Effect of Coriolus versicolor Fruiting Body on STZ-Induced ICR Diabetic Mice
Table 1
The effect of 28-day CVFB treatment on the water intake, food intake, body weights, and organ index of STZ-induced ICR diabetic mice (n = 11).
No.
NS
DC
LD
MD
HD
PC
Water intake (ml)
28 days
0
7.9 ± 0.2
45.6 ± 2.2
44.2 ± 2.6
50.8 ± 1.4
44.2 ± 2.4
46.5 ± 2.3
7
5.0 ± 0.6
46.9 ± 1.3
47.7 ± 0.8
50.0 ± 2.6
50.0 ± 4.2
50.0 ± 1.2
a
14
5.0 ± 0.6
55.6 ± 0.9
59.4 ± 0.8
64.1 ± 1.7
56.3.0 ± 4.6
56.9 ± 1.4
21
6.7 ± 1.2
58.1 ± 0.7
57.5 ± 1.9
66.7 ± 2.3
61.3 ± 5.0
60.0 ± 1.5
28
4.2 ± 0.3
62.5 ± 0.6
63.1 ± 1.1
66 ± 1.4
61.9 ± 3.7
61.8 ± 1.6
Food intake (g)
28 days
0
9.4 ± 0.1
11.9 ± 0.8
10.8 ± 0.5
11.3 ± 0.2
10.7 ± 0.4
10.2 ± 0.8
7
5.2 ± 0.2
11.0 ± 0.8
9.8 ± 0.3
9.2 ± 0.4
10.1 ± 0.6
8.1 ± 0.3
b
14
5.8 ± 0.2
10.2 ± 0.1
11.6 ± 0.3
11.7 ± 0.3
11.3 ± 0.5
10.2 ± 0.7
21
5.5 ± 0.2
10.5 ± 0.2
10.4 ± 0.3
10.1 ± 0.4
9.8 ± 0.4
9.2 ± 0.9
28
4.5 ± 0.1
11 ± 0.2
11.6 ± 0.2
11.0 ± 0.2
10.3 ± 0.3
9.1 ± 0.3
Body weights (g)
28 days
0
23.1 ± 0.8
25.2 ± 1.0
24.9 ± 0.9
24.0 ± 0.8
25.9 ± 1.4
25.4 ± 1.1
7
28.7 ± 0.6
23.1 ± 1.0
24.3 ± 0.7
24.2 ± 0.8
26.1 ± 1.0
24.1 ± 1.1
c
14
33.4 ± 0.6
26.6 ± 1.0
26.2 ± 0.9
26.9 ± 1.0
29.4.0 ± 1.3
28.6 ± 0.7
21
31.6 ± 0.7
24.9 ± 1.0
28.25 ± 0.8
27.9 ± 0.8
25.9 ± 1.2
25.2 ± 0.4
28 growth rate (%)
36.5 ± 0.858.0
25.1 ± 1.0–0.4
29.3 ± 0.817.7
29.7 ± 0.923.8
30.5 ± 1.417.8
29.8 ± 0.917.3
Organ index (mg/g)
Liver
49.4 ± 1.8
53.0 ± 1.9
50.8 ± 1.9
47.3 ± 1.6
48.9 ± 1.8#
49.8 ± 0.8
Kidney
14.1 ± 0.3###
18.4 ± 0.4
19.9 ± 0.4##
18.6 ± 0.5
17.2 ± 0.4#
17.6 ± 0.5
d
Spleen
2.8 ± 0.3###
1.7 ± 0.04
1.9 ± 0.1
1.6 ± 0.1
1.5 ± 0.1
2.0 ± 0.2
Thymus
1.0 ± 0.1###
0.4 ± 0.03
0.7 ± 0.1##
0.5 ± 0.1
0.4 ± 0.1
0.4 ± 0.04
Pancreas
6.3 ± 0.3
5.9 ± 0.3
5.9 ± 0.4
5.6 ± 0.2
6.1 ± 0.4
6.2 ± 0.3
Heart
4.6 ± 0.1###
3.6 ± 0.1
3.9 ± 0.1#
3.5 ± 0.1
3.8 ± 0.1
3.7 ± 0.2
< 0.05, < 0.01, and < 0.001 are the comparisons between within the group and day 0; # < 0.05, ## < 0.01, and ### < 0.001 versus DC group. Growth rate: body weights increment (day 28–day 0)/body weight (day 0)×100%.
