Research Article

Development and Validation of the Random Forest Model via Combining CT-PET Image Features and Demographic Data for Distant Metastases among Lung Cancer Patients

Table 2

The performance of the three random forest models.

Random forest modelsDatasetPPV (95% CI)NPV (95% CI)AUC (95% CI)Accuracy (95% CI)

CT demographic dataTraining set0.556 (0.393–0.718)0.949 (0.905–0.993)0.880 (0.807–0.953)0.843 (0.782–0.905)
CT demographic dataTesting set0.429 (0.169–0.688)0.833 (0.700–0.967)0.716 (0.531–0.902)0.705 (0.570–0.839)
PET demographic dataTraining set0.410 (0.286–0.533)1.000 (1.000–1.000)0.917 (0.865–0.969)0.731 (0.656–0.806)
PET demographic dataTesting set0.381 (0.173–0.589)0.870 (0.732–1.000)0.802 (0.633–0.970)0.636 (0.494–0.779)
CT-PETTraining set0.523 (0.375–0.670)0.967 (0.930–1.000)0.904 (0.850–0.959)0.821 (0.756–0.886)
CT-PETTesting set0.364 (0.079–0.648)0.818 (0.687–0.950)0.797 (0.666–0.928)0.705 (0.570–0.839)
CT- PET demographic dataTraining set0.714 (0.547–0.882)0.953 (0.912–0.993)0.923 (0.873–0.973)0.903 (0.853–0.953)
CT-PET demographic dataTesting set0.750 (0.450–1.000)0.861 (0.748–0.974)0.873 (0.757–0.990)0.841 (0.733–0.949)

Note. CT: computed tomography; PET: positron emission tomography; CI: confidence interval; PPV: positive predictive value; NPV: negative predictive value; AUC: area under the curve.