Establishment and Validation for Predicting the Lymph Node Metastasis in Early Gastric Adenocarcinoma

Table 3

Univariate and multivariate logistic regression analyses of factors associated with LNM.

Variables	Univariate analysis		Multivariate analysis
	OR (95% CI)		OR (95% CI)
Age	0.99 (0.97–1.01)	0.193	—	—
Gender
Female	Ref
Male	1.12 (0.73–1.73)	0.606	—	—
T stage
T1a	Ref		Ref
T1b	5.02 (2.72–9.26)	<0.001	3.84 (2.04–7.21)	<0.001
Primary site
Lower	Ref
Overlap	1.19 (0.55–2.57)	0.661	—	—
Middle	0.95 (0.60–1.51)	0.836	—	—
Upper	0.74 (0.16–3.46)	0.699	—	—
Type
Diffuse	Ref
Intestinal	0.65 (0.30–1.40)	0.274	—	—
Others	0.95 (0.35–2.53)	0.911	—	—
Tumor size
<1	Ref
1-	3.95 (1.45–10.75)	0.007	2.70 (0.97–7.54)	0.058
2-	4.73 (1.73–12.90)	0.002	3.07 (1.10–8.61)	0.033
3-	6.88 (2.38–19.89)	<0.001	4.73 (1.58–14.13)	0.005
4-	9.23 (3.43–24.84)	<0.001	5.75 (2.08–15.92)	<0.001
Grade
I	Ref		Ref
II	2.80 (1.14–6.91)	0.025	2.04 (0.80–5.21)	0.137
III	4.68 (1.94–11.32)	<0.001	3.19 (1.27–8.00)	0.014

Note: LNM: lymph node metastasis; OR: odds ratio; CI: confidence interval; Ref: reference.