Research Article
[Retracted] Serum Expression Level of MicroRNA-122 and Its Significance in Patients with Hepatitis B Virus Infection
Table 1
Clinical data of four groups in study subjects.
| | Clinical data | Healthy (N = 10) | CHB (N = 11) | Cirrhosis (N = 26) | HCC (N = 16) | P value |
| | Age | 61.5 ± 5.1 | 53.1 ± 3 | 59.1 ± 2.5 | 62.3 ± 3.5 | 0.447 | | Male (%) | 60 | 54.5 | 80.8 | 75 | 0.336 | | Hb | 134.1 ± 26.71a,b | 133.64 ± 16.11c,d | 103.31 ± 31.24a,c | 101.31 ± 30.19b,d | 0.002 | | WBC | 5.33 ± 1.49 | 6.29 ± 2.71 | 97.04 ± 60.59a,c | 118.75 ± 65.65b,d | ≤0.01 | | PLT | 195.89 ± 90.51a,b | 211.64 ± 79.08c,d | 4.31 ± 2.03 | 5.96 ± 4.25 | 0.158 | | Ur | 6.41 ± 4.71 | 4.75 ± 1.23 | 5.98 ± 2.41 | 8.23 ± 5.29 | 0.092 | | Cr | 80.44 ± 33.33 | 71.00 ± 17.47 | 71.54 ± 14.54 | 101.25 ± 54.27 | 0.032 | | AST | 33.10 ± 26.43 | 163.00 ± 315.03 | 40.96 ± 25.22 | 150.86 ± 225.52 | 0.081 | | ALT | 27.22 ± 25.03 | 211.73 ± 407.64 | 34.73 ± 38.92 | 100.38 ± 168.27 | 0.068 | | TB | 14.51 ± 7.49a | 13.12 ± 8.15b | 27.32 ± 16.59a,b | 50.28 ± 56.77 | 0.010 | | DB | 5.86 ± 3.32a | 7.00 ± 5.23b | 14.74 ± 11.54a,b | 30.68 ± 40.11 | 0.017 | | AKP | 85.67 ± 52.38 | 73.55 ± 36.53 | 83.50 ± 37.63 | 162.56 ± 130.3 | 0.050 | | Alb | 44.67 ± 4.39 | 36.36 ± 4.55 | 35.42 ± 7.08 | 29.50 ± 7.23 | ≤0.01 | | AFP | 2.49 ± 1.51 | 40.96 ± 72.78 | 9.56 ± 15.59 | 610.48 ± 591.12 | ≤0.01 |
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Data are mean ± SD. CHB, chronic hepatitis B; HCC, hepatocellular carcinoma; WBC, white blood cell; PLT, platelet; Ur, urea; Cr, creatinine; AST, aspartate aminotransferase; ALT, alanine aminotransferase; TB, total bilirubin; DB, direct bilirubin; AKP, alkaline phosphatase; Alb, albumin; AFP, alpha-fetoprotein; a, b, c, and d: , significant between-group differences. |