Dysfunctional Network and Mutation Genes of Hypertrophic Cardiomyopathy

Figure 4

Mutations of the expressed genes in HCM samples. (a) The summary of the mutations in all samples. (b) Mutations in the top 10 genes. Genes are ordered by their mutation frequency and the mutation rate in the samples. (c) Transition and transversion plot displaying the distribution of SNVs in HCM classified into six transition and transversion events. Stacked bar plot shows the distribution of mutation spectra for every sample. (d) Word cloud plot for mutated genes. Size of each gene is proportional to the total number of samples in which it is mutated.

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