4-Methoxydalbergione Elicits Anticancer Effects by Upregulation of GADD45G in Human Liver Cancer Cells

<div>4MOD induces apoptosis of HCC cells. (a) Flow cytometry on apoptosis rates of SK-HEP-1 cells exposed to 0, 20, and 40 <i>μ</i>M of 4MOD for 48 h. The histogram shows statistical analysis for the apoptotic cells. (b) Flow cytometry on apoptosis rates of HuH-7 cells exposed to 0, 10, and 20 <i>μ</i>M of 4MOD for 48 h. The histogram shows statistical analysis for the apoptotic cells. ns, <span class="nowrap"><svg height="11.7782pt" id="M8" style="vertical-align:-3.42938pt" version="1.1" viewbox="-0.0498162 -8.34882 44.5261 11.7782" width="44.5261pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M570 304C570 398 525 448 414 448C385 448 343 445 312 434L329 511L321 518C297 504 262 482 244 460L233 411C195 397 159 381 128 358L135 332C160 347 189 360 224 373L111 -147C97 -210 84 -218 17 -231L13 -257L254 -247L259 -218L233 -216C183 -212 177 -202 189 -142L218 -1C238 -10 266 -12 283 -12C351 3 429 48 483 105C543 168 570 242 570 304ZM482 289C482 161 380 33 304 33C278 33 248 51 233 69L303 396C326 400 352 403 369 403C428 403 482 380 482 289Z"></path></g><g transform="matrix(.013,0,0,-0.013,11.342,0)"><path d="M531 285V335L57 550V494L473 310L57 127V71L531 285ZM531 -40V10H57V-40H531Z"></path></g><g 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Journal of Healthcare Engineering

fig3

Figure 3

Figure 3: 4-Methoxydalbergione Elicits Anticancer Effects by Upregulation of GADD45G in Human Liver Cancer Cells 