The Effect of Calcipotriol on the Expression of Human Defensin-2 and LL-37 in Cultured Human Keratinocytes
Figure 4
The expression of LL-37 mRNA in the keratinocytes was also upregulated when stimulated with LPS, TNF-, and UVB irradiation at 6, 12, and 24 hours. Similar to the hBD-2 results, LL-37 mRNA expression decreased after treatment with calcipotriol. *: Statistically significant between UV and CA UV (). : Statistically significant between LPS and CA LPS (). : Statistically significant between TNF-s and CA TNF-a ().