Expansion and Activation Kinetics of Immune Cells during Early Phase of GVHD in Mouse Model Based on Chemotherapy Conditioning
Figure 1
Bone marrow and spleen cellularity in allogeneic and syngeneic transplanted mice. Female BALB/c mice were transplanted with and BM and SP cells, respectively, from male C57BL/6 or BALB/c mice as allogeneic or syngeneic setting. Bone marrow (a) and spleen (b) cellularity at different time points after conditioning and transplantation. (a) Bone marrow cellularity calculated based on total cells extracted from both femurs. (b) Spleen cellularity determined based on 100 mg of spleen tissue. (◆): allogeneic group, (◊): syngeneic group and (O): control mice. All values are mean ± SE for 4 to 6 animals in each group per time point. Differences were analyzed statistically employing U-test, compared between groups ().
