Research Article

Expansion and Activation Kinetics of Immune Cells during Early Phase of GVHD in Mouse Model Based on Chemotherapy Conditioning

Figure 5

Cytokine levels in the serum of GVHD developing mice. Inflammatory cytokine levels were measured in the serum of allogeneic transplanted BALB/c mice at different time points before and after BMT. (a) IL-2, (b) IFN gamma, and (c) TNF-alfa levels in the serum of GVHD mice. All of the inflammatory cytokines showed maximum level 5 days after BMT in GVHD mice. Serum level of these cytokine was not detectable in syngeneic setting. (ā—†): allogeneic setting Differences were analyzed statistically employing U-test, compared between groups ( ).
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