Effects of Splenectomy on Spontaneously Chronic Pancreatitis in aly/aly Mice
Figure 1
Chronic inflammatory changes of splenectomized (Sp) and sham aly/aly mice at the ages of 20, 30, and 40 weeks old, respectively. The pancreas was histopathologically examined (refer to Figure 2). Grading of inflammatory lesions of the pancreas: 0, no visible change; (1), focal accumulation of lymphoid cells; (2), focal accumulation of lymphoid cells with evidence of tissue damage; (3), extensive lymphoid cell infiltration with tissue damage (<30%); (4), replacement by adipose tissue (>30%).
