Interferon Alpha on Expression of hTERT mRNA in Peripheral Blood Mononuclear Cells of Patients with Chronic Hepatitis B

Table 3

Comparison of mean NhTERT mRNA levels between IFNα-treated subgroups.

	ALT(IU/L)		HBV DNA (log copies/mL)		HBeAg status*
	<40	≥40	<3 log	≥3 log	e-Ag (+)	e-Ag (−)
No.	23	14	18	19	17	14
Mean NhTERT	0.967	1.007	1.011	0.950	0.910	1.010
mRNA level (×10^-3)	±0.105	±0.095	±0.084	±0.105	±0.111	±0.100
t-value	1.172		1.955		2.595
P-value	.249		.059		.015

Note. *subgroup: 31 cases of HBeAg positive CHB; e-Ag (+): without HBeAg loss; (−): with HBeAg loss.