Longitudinal Analysis of Tetanus- and Influenza-Specific IgG Antibodies in Myeloma Patients

Table 2

correlation of FLU-antibodies and TT-antibodies with clinical parameters.

Parameter	Stratification	N	Mean (FLU)	Mean (TT)
Gender	men	115	1,042	1,202
	women	75	0,918	1,133
Age	≤ 60 years	122	0,969	1,253^∗
	> 60 years	67	1,034	1,023^∗
Hemoglobin	low	157	1,022	1,181
	normal	30	0,859	1,087
Albumin	<35 g/l	27	0,877	0,699^∗
	≥35 g/l	158	1,015	1,247^∗
LDH	≤225 U/I	137	1,007	1,156
	>225 U/I	49	0,972	1,194
Calcium	≤2,63 mmol/l	182	0,995	1,145^∗
	>2,63 mmol/l	2	1,040	2,470^∗
Creatinin	≤1,3 mg/dL	146	0,990	1,123
	>1,3 mg/dL	37	1,035	1,355
IgG (for IgG myeloma)	≤16 g/l	44	1,018	1,248^∗
	>16 g/l	41	0,746	0,874^∗
IgG (for IgA myeloma)	≤16 g/l	39	0,994	1,103
	>16 g/l	4	0,883	0,870
IgA (for IgA myeloma)	≤4 g/l	17	0,986	1,151
	>4 g/l	26	0,982	1,034
Kappa-light chains	≤3,7 g/l	14	1,116	1,557
	>3,7 g/l	0	—	—
Lambda-light chain	≤2 g/l	12	1,164	1,007
	>2 g/l	1	0,210	0,030
Deletion 13q14	positive	46	0,900	1,014
	negative	117	1,038	1,218
Deletion 17p13	positive	13	1,058	1,350
	negative	150	0,989	1,142
Translocation t (4; 14)	positive	9	0,933	0,793
	negative	153	0,998	1,178
β2-Microglobulin	≤3 mg/l	60	0,970	1,200
	>3 mg/l	32	0,807	0,942
GvHD	positive	42	0,885	0,965
	negative	21	0,893	1,172
Plasma cells in BM	≤10%	68	0,978	1,241
	>10%	37	0,949	1,006

^∗indicates a statistically significant result (𝑃<0.05); if not otherwise specified, differences between groups are not significant.