BPI-ANCA and Long-Term Prognosis among 46 Adult CF Patients: A Prospective 10-Year Follow-Up Study

Table 3

Lung function, BPI-ANCA, and outcome. Patients divided into groups based lung function and IgA BPI-ANCA levels at baseline, and subsequent end-points during followup.

Lung function	FEV1 pred > 80%			FEV1 pred 50–80%			FEV1 pred < 50%
BPI-ANCA group	BPI−	BPI+	BPI++	BPI−	BPI+	BPI++	BPI−	BPI+	BPI++
Inclusion (𝑛)	11	5	0	5**	7*	5	1	6	6
5 years % with endpoint	0	0	—	20%	14.3%	20%	0	33%	33%
(𝑛 with endpoint)				(1)	(1*)	(1)		(2)	(2)
10 years % with endpoint	0	0	—	40%	28.6%	40%	0	50%	100%
(𝑛 with endpoint)				(2**)	(2*)	(2)		(3)	(6)
Last followup, % with endpoint	0	0	—	40%	42.8%	60%	100%	66.7%	100%
(𝑛 with endpoint)				(2**)	(3*)	(3)	(1)	(4)	(6)

∗Patient with colon cancer.
**Patient with Burkholderia cepacia.