Deranged Bioenergetics and Defective Redox Capacity in T Lymphocytes and Neutrophils Are Related to Cellular Dysfunction and Increased Oxidative Stress in Patients with Active Systemic Lupus Erythematosus

<table>Comparison of 24-hour urinary excretion of <i>N</i>-benzoyl-glycyl-<i>Nε</i>-(hexanoyl)lysine (<i>Nε</i>-HEL) and 8-hydroxy-2-deoxyguanosine (8-OHdG), intracellular basal lactate levels, and ATP production of T lymphocytes and PMN from normal individuals, non-SLE patients, and patients with active SLE. (a) Urinary <i>Nε</i>-HEL excretion denoted by pmole/mg urine creatinine (Ucre). (b) Urinary 8-OHdG excretion denoted by ng/mg Ucre. (c) Intracellular basal lactate levels. (d) ATP production.</table>

Journal of Immunology Research

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Figure 1

Figure 1: Deranged Bioenergetics and Defective Redox Capacity in T Lymphocytes and Neutrophils Are Related to Cellular Dysfunction and Increased Oxidative Stress in Patients with Active Systemic Lupus Erythematosus 

Figure 1 | Deranged Bioenergetics and Defective Redox Capacity in T Lymphocytes and Neutrophils Are Related to Cellular Dysfunction and Increased Oxidative Stress in Patients with Active Systemic Lupus Erythematosus 