Systemic-Lupus-Erythematosus-Related Acute Pancreatitis: A Cohort from South China

Table 3

Comparison of demographic and clinical characteristics between SLE-related severe acute pancreatitis (SAP) and mild acute pancreatitis (MAP).

	SAP (𝑛=8)	MAP (𝑛=19)	𝑃 value
Demographic characteristics
Female	7 (87.50%)	18 (94.74%)	0.513
Age of onset AP (y)	19.63±10.88	30.05±13.25	0.016
Interval between onset of SLE and AP (m)	23.38±28.25	44.36±64.73	0.822
Early AP (⩽1 year)	5 (62.50%)	9 (47.37%)	0.678
SLEDAI score at onset of AP	22.13±6.24	21.53±11.77	0.44
SLICC/ACR damage index	1.25±0.89	1.16±0.96	0.854
Number of organs involved	5.75±1.28	5.68±1.70	0.893
Intensive therapy of GC/ISA	5 (62.50%)	11 (57.89%)	1
Mortality	6 (75%)	4 (21.05%)	0.014
Clinical characteristics
Fever	8 (100.00%)	13 (68.42%)	0.136
Mucocutaneous involvement	6 (75.00%)	12 (63.16%)	0.676
Articular involvement	3 (37.50%)	10 (52.63%)	0.678
Serositis	5 (62.50%)	10 (52.63%)	0.696
Neuropsychiatric involvement	2 (25.00%)	5 (26.32%)	1
Renal involvement	7 (87.50%)	15 (78.95%)	1.0
Laboratory findings
Serum amylase^*	18.09±18.15	7.46±5.88	0.077
Serum lipase^*	8.53±3.14	7.63±5.45	0.616
Elevated serum transaminase	7 (87.5%)	11 (57.89%)	0.201
Thrombocytopenia	8 (100%)	10 (52.63%)	0.026
Leucopenia	7 (87.50%)	6 (31.58%)	0.013
Positive anti-dsDNA	8 (100.00%)	16 (84.21%)	0.532
Positive anti-Sm	1/7 (14.29%)	5/14 (35.71%)	0.613
Low C3	8/8 (100.00%)	18/18 (100.00%)	1
Low C4	7/8 (87.50%)	14/18 (77.78%)	1
Anti-Ro	2/7 (28.57%)	11/14 (78.57%)	0.056
Anti-La	1/7 (14.29%)	6/14 (42.86%)	0.337

^*Times in excess of the upper limit of normal (ULN).