Journal of Immunology Research

Review Article

Myeloid-Derived Suppressor Cells Participate in Preventing Graft Rejection

Summary of phenotype of MDSCs in tumors and transplantation models.


Tumour type	Reported phenotype	References

Renal cell carcinoma	CD11b⁺/CD14^-/CD33⁺/CD15⁺
Renal cell carcinoma	CD66b⁺/VEGF1⁺	Rodriguez et al. [16]
Non small cell lung cancer	CD11b⁺/CD14^-/CD15⁺/CD33⁺	Liu et al. [17]
Colon carcinoma	Lin^-/HLA-DR^-/CD33⁺/CD11b⁺	Diaz-Montero et al. [18]
Breast carcinoma	Lin^-/HLA-DR^-/CD33⁺/CD11b⁺	Diaz-Montero et al. [18]
Prostate cancer	CD14⁺/HLA-DR^low/neg	Vuk-Pavlović et al. [19]
Malignant melanoma	CD14⁺/CD11b⁺/HLA-DR^low/neg	Filipazzi et al. [20]
Malignant melanoma	CD80⁺/CD86⁺	Poschke et al. [21]
Hepato-cellular carcinoma	CD14⁺/HLA-DR^low/neg	Hoechst et al. [22, 23]
Hodgkin lymphoma (HL)	CD11b⁺, CD13⁺, CD34⁺, CD14-, CD45+	Parrinello et al. [24]
Non hodgkin lymphoma	CD14⁺/HLA DR^low/neg/CD120^low	Lin et al. [25]
Myelodysplastic syndrome (MDS)	LIN^-/HLA-DR^-/CD33⁺	Wei et al. [26]

Transplantation model	Reported phenotype	References

Rat kidney allograft	CD11b⁺CD6^-CD80/86⁺NKRP-1⁺	Dugast et al. [15]
Mouse skin allograft	CD40⁺/CD80⁺/F480⁺/IL-4Rα ⁺	Adeegbe et al. [27]
	CD11b⁺/Gr1⁺	Zhang et al. [28],
		De Wilde et al. [29]
Mouse hepatic islet allograft	CD11b⁺/CD45⁺	Chou et al. [30]
Mouse cardiac allograft	CD11b⁺/Gr-1^int/F4/80⁺	Turnquist et al. [31]