Propofol Reduces Lipopolysaccharide-Induced, NADPH Oxidase (NOX2) Mediated TNF-α and IL-6 Production in Macrophages
Figure 7
Effect of propofol pretreatment on LPS-induced NADPH oxidase expression. Cells were pretreated with dimethyl sulfoxide (DMSO) or propofol for 40 min and then stimulated with LPS for 8 h. (a) Protein expression of oxidase subunits was analyzed by Western blot analysis of whole cell lysates. (b, c, and d) The levels of subunit protein expression were quantified by measuring band intensities and displayed as fold increase relative to β-actin. Each value represents the means ± SD for . # and * indicate that a value significantly () differs from without both propofol and LPS or only LPS treated groups, respectively.
