Research Article

HLA-G Expression Is an Independent Predictor for Improved Survival in High Grade Ovarian Carcinomas

Table 1

Patient characteristics.

Baseline characteristicsAll patients

Mean age, years (SD)61 (11.7)
FIGO stage
 I8 (5%)
 II7 (4%)
 III125 (74%)
 IV29 (17%)
Histologic classification
 High grade serous141 (83%)
 Undifferentiated28 (17%)
Residual disease after debulking surgery
 No macroscopic tumour37 (22%)
 Less than 1 cm residual disease46 (27%)
 1 cm or more residual disease86 (51%)
Kind of debulking surgery
 PDS134 (79%)
 IDS35 (21%)
Tissue origin
 Ovary141
 Metastases28
Kind of chemotherapy given
 None9 (5%)
 Single drug platinum5 (3%)
 Multidrug carboplatin/paclitaxel123 (19%)
 Multidrug with platinum32 (73%)
 Amount of cycles6 (5–7)
Platinum sensitivity
 Refractory disease 34 (20%)
 Platinum resistant disease36 (21%)
 Partial chemosensitive25 (15%)
 Platinum sensitive disease65 (38%)

Refractory disease: recurrence occurred during chemotherapy treatment; platinum resistant disease: recurrence occurred within 6 months after the last cycle of chemotherapy; partial platinum sensitive disease: recurrence occurred after 6 months or within 1 year after last cycle of platinum based chemotherapy; platinum sensitive disease: recurrence occurred more than 1 year after the last cycle of chemotherapy.