Research Article
HLA-G Expression Is an Independent Predictor for Improved Survival in High Grade Ovarian Carcinomas
Table 2
Correlation of HLA-A, HLA-B/C, HLA-G, and HLA-E expression with clinical parameters.
| | HLA-A | HLA-B/C | HLA-E | HLA-G | | Normal expression | Downregulation | | Normal expression | Downregulation | | Upregulation | Normal expression | | Upregulation | Normal expression | |
| (%) | 51 (36) | 91 (64) | | 29 (17) | 124 (83) | | 124 (83) | 28 (17) | | 81 (53) | 71 (47) | | Variables | | | | | | | | | | | | | Age | | | | | | | | | | | | | <60 | 30 | 42 | 0.15 | 14 | 63 | 0.78 | 65 | 10 | 0.26 | 40 | 38 | 0.61 | >60 | 21 | 49 | | 12 | 61 | | 59 | 15 | | 33 | 41 | | FIGO stage | | | | | | | | | | | | | Stages I-IIA | 4 | 4 | 0.39 | 1 | 6 | 0.83 | 5 | 2 | 0.39 | 3 | 3 | 0.87 | Stage >IIB | 47 | 87 | | 25 | 118 | | 119 | 23 | | 78 | 68 | | Residual tumor | | | | | | | | | | | | | No residual | 18 | 14 | 0.006 | 11 | 22 | 0.006 | 27 | 4 | 0.51 | 23 | 10 | 0.033 | Any residual | 33 | 77 | | 15 | 102 | | 97 | 21 | | 58 | 61 | | Platinum sensitivity | | | | | | | | | | | | | Resistant | 15 | 40 | 0.08 | 9 | 48 | 0.66 | 52 | 9 | 0.66 | 25 | 35 | 0.014 | Sensitive | 33 | 46 | | 15 | 65 | | 66 | 14 | | 53 | 32 | |
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