Lipopolysaccharide Increases Immune Activation and Alters T Cell Homeostasis in SHIV_B’WHU Chronically Infected Chinese Rhesus Macaque

Figure 2

LPS administration in chronically SHIV_B’WHU-infected Ch-RMs. LPS induces a transient increase in the VL. The dashed line indicates the limit of detection at 100 copies/mL plasma (a), a transient decrease in the absolute number of CD4⁺ T cells (b), an increase in CD8⁺ T cells (c), a decrease in CD20⁺ B cells (d), an increase in levels of CD14⁺ cells (e), and an increase in plasma sCD14 (f). Ch-RMs were intravenously injected twice with LPS at 50 μg/kg body weight at day 0 and day 14 (arrows).

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