Mesenchymal Stem Cells Immunosuppressed IL-22 in Patients with Immune Thrombocytopenia via Soluble Cellular Factors

<div>UC-MSCs immunosuppressed IL-22 by soluble cellular factors but not PGE2. (a) UC-MSCs inhibited CD4<sup>+</sup>T cells secreting IL-22 and the expression of IL-22 mRNA; (b) the immunoregulation of UC-MSCs on IL-22 was mediated by soluble cellular factors; (c) PGE2 did not involve in the immunoregulation of UC-MSCs on IL-22. 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Journal of Immunology Research

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Figure 4

Figure 4: Mesenchymal Stem Cells Immunosuppressed IL-22 in Patients with Immune Thrombocytopenia via Soluble Cellular Factors 