Experimental Autoimmune Encephalomyelitis Development Is Aggravated by Candida albicans Infection

Figure 6

Candida specific T cells contribute to elevated production of encephalitogenic cytokines in the CNS. CNS eluted cells were restimulated with MOG or heat-killed C. albicans and TNF-α (a), IL-6 (b), IL-17 (c), IFN-γ (d), IL-2 (e), and IL-10 (f) levels were measured by ELISA. The results are expressed as median, 25–75% (box), and minimum-maximum (error bars) of 6 to 7 mice/group. Mann-Whitney test, and indicate statistical difference between EAE and EAE+Ca groups under the same in vitro stimulation.

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