Branched Polyethylenimine-Superparamagnetic Iron Oxide Nanoparticles (bPEI-SPIONs) Improve the Immunogenicity of Tumor Antigens and Enhance Th1 Polarization of Dendritic Cells

Figure 1

Uptake of branched polyethylenimine-superparamagnetic iron oxide nanoparticles (bPEI-SPION) by U266 cells. (a) Ferric mass contained in 5 × 10⁵ U266 cells after exposure to various amount of bPEI-SPION for 1 h. (b) The presence of nanoparticles intracellularly was confirmed by confocal microscopy in which red and blue indicate bPEI-SPION and nucleus, respectively. Data are representative of four independent experiments ().

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