Autoantibodies Affect Brain Density Reduction in Nonneuropsychiatric Systemic Lupus Erythematosus Patients

Figure 1

GMD/WMD reduction and the correlation between GMD with disease activity in non-NPSLE. (a) Significantly reduced GMD and WMD in SLE compared with CTLs; (b) negative correlation between GMD and the SLEDAI score of SLE. SLE: systemic lupus erythematosus; CTL: control; GMD: mean whole brain grey matter density; WMD: mean whole brain white matter density; SLEDAI: systemic lupus erythematosus disease activity index. , .

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