Exposure of Monocytes to Lipoarabinomannan Promotes Their Differentiation into Functionally and Phenotypically Immature Macrophages

Figure 3

Frequency of CD14⁺CD68⁺ macrophages decreases when monocytes are exposed to LAM. Pure monocytes were incubated with LAM for 24–120 h at 37°C. All cells were recovered on day 7. Representative zebra plots for CD68 versus CD14 (a). A percentage of CD68⁺, CD14⁺CD68⁺, and CD14⁻CD68⁻ are shown. Data are representative of five independent experiments. Box plot indicates median ± IQR (5–95). , . Kruskal-Wallis and Dunn post hoc tests compared to unexposed monocytes.

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