Association of Toll-Like Receptor 3 Single-Nucleotide Polymorphisms and Hepatitis C Virus Infection
Table 1
Baseline and clinical characteristics of HCV-infected patients and healthy control subjects.
Variable
Chronic HCV
Liver cirrhosis
HCC
Healthy control
value
Age (yrs.)
43.23 ± 22.25
53.20 ± 19.79
63.23 ± 10.70
30.79 ± 8.90
<0.0001
Sex
Male count (%)
214 (49%)
44 (50%)
18 (47.4%)
577 (96.3%)
<0.0001
Female count (%)
223 (51%)
44 (50%)
20 (52.6%)
22 (3.7%)
29.2 (25.67–33.39)
30.06 (26.22–33.06)
25.99 (21.89–31.39)
0.804
Platelet
230 (178.75–282.25)
163.5 (108.50–205.50)
104.00 (51.50–139.00)
<0.0001
87.58 ± 119.76
93.18 ± 68.88
114.33 ± 31.78
0.738
55.36 ± 41.87
77.28 ± 47.20
91.33 ± 24.58
<0.0001
113.37 ± 78.91
133.66 ± 90.04
147.00 ± 96.70
0.072
HCV viral Load
6.04 (5.42–6.53)
6.08 (5.57–6.45)
5.98 (2.79–7.24)
0.552
are expressed as median interquartile range (25th–75th). are expressed as mean ± SD. : nonparametric test and one-way ANOVA for continuous data and Chi square test for categorical data. ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase.
