De Novo Donor-Specific HLA Antibodies Developing Early or Late after Transplant Are Associated with the Same Risk of Graft Damage and Loss in Nonsensitized Kidney Recipients

Figure 3

Histological analysis in 30 graft biopsies obtained from 13 recipients displaying early-onset dnDSAs (dark grey bars) and 17 recipients positive for late-onset dnDSAs (light grey bars). The biopsy findings were analyzed both individually (i, t, ptc, g, ci, ct, cg, cv, v) and in functional clusters (ptc + g referring to microcirculation inflammation, ptc + g + cg to microcirculation lesions, i + t to tubulointerstitial inflammation, and ci + ct to tubulointerstitial scarring). Data are presented as the mean ± standard error. For each parameter, no significant difference was observed between the two groups.