Research Article

Beneficial Effects of Prebiotic Saccharomyces cerevisiae Mannan on Allergic Asthma Mouse Models

Figure 8

Intranasal SC-MN pretreatment inhibited the OVA-induced increase in small airways ASM, trachealis muscle mass, and number of ASM nuclei of small airways in huASM-MRC2 mice. (a) SC-MN inhibited the trachealis muscle remodeling induced by OVA (day 52) (); (b) H&E staining of trachea cross section; (c) small airway ASM area (day 45) ( = 5-6); (d) SC-MN inhibition of the increased small airway ASM nuclei in allergic transgenic mice (). versus OVA-challenged group with saline pretreatment.
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