RNA-Seq Based Transcriptome Analysis of the Type I Interferon Host Response upon Vaccinia Virus Infection of Mouse Cells

Figure 3

IPA analysis of differentially expressed host genes in VACV-infected cells. The list of SDEGs identified after VACV infection was used in a pathway enrichment analysis with IPA software. The 40 most significant pathways identified at 4 hpi (a) and 9 hpi (b) after VACV infection are shown. The -axis represents the value, indicating the significance of enrichment for the corresponding gene set. The values are plotted in a negative log₁₀ scale.

(a)

(b)