Sex Differences in Correlation with Gene Expression Levels between Ifi200 Family Genes and Four Sets of Immune Disease-Relevant Genes

Figure 2

Gene network and sex difference of Ifi family genes with important immune-related genes in the spleen. (a) Gene network of Ifi family genes in male mice. The 21 nodes in the graph below show the selected traits. All nodes are displayed. The 25 edges between the nodes, filtered from the 210 total edges and drawn as curves, and the node labels are drawn with an 18.0-point font, and the edge labels are drawn with a 15.0-point font. (b) Gene network of Ifi family genes in female mice. The 23 nodes in the graph below show the selected traits. The 36 edges between the nodes, filtered from the 253 total edges and drawn as curves, and the node labels are drawn with a 16.0-point font, and the edge labels are drawn with a 16.0-point font. (c) Sex difference for correlation of expression levels between Ifi202b and important immune-related genes in the spleen. The numbers on the vertical bar indicate the scale of values between the expression level of Ifi202b and each gene listed at the bottom of the figure. Female and male mice are indicated with red (female) and blue (male) color. Black bars indicate genes that showed the most sex difference when its expression level is correlated with that of Ifi202b.

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