Two-Parametric Immunological Score Development for Assessing Renal Involvement and Disease Activity in Systemic Lupus Erythematosus

Figure 3

Association of single markers anti-dsDNA, anti-C1q, and anti-Ku antibodies (a) and oligoparametric models (b) with disease activity, lupus nephritis, and lupus nephritis activity. The number of patients and percentage of positive patients are indicated above the graph. The y-axis is shown in logarithmic scale. Error bars indicate the 95% confidence intervals. The term optimized pertains to a use of an alternative cut-off (other than the manufacturer’s cut-off) which gave the best likelihood ratios in Figure 2.

(a)

(b)