Analysis of ROR1 Protein Expression in Mice with Reconstituted Human Immune System Components

Figure 1

NOD-scid IL2rg^−/− (NSG) mice injected with fetal liver-derived CD34⁺ hematopoietic progenitor cells were reconstituted with human immune cells. Peripheral blood of reconstituted NSG mice was analyzed 3 months after injection of human hematopoietic progenitor cells. The frequencies of different immune cell compartments are indicated. Frequencies of human CD45⁺ cells within the leukocyte gate, frequencies of CD19⁺ B cells, NKp46⁺ NK cells, and CD3⁺ T cells within human CD45⁺ cells, and frequencies of CD4⁺ and CD8⁺ T cells within CD3⁺ cells are shown. Horizontal lines represent the mean and SD. Data are from 3 different reconstitution cohorts with CD34⁺ cells derived from 3 different fetal liver tissues.