Analysis of ROR1 Protein Expression in Mice with Reconstituted Human Immune System Components

Figure 2

ROR1 expression on B cells in huNSG mice. (a) Flow cytometry staining of CD19⁺ and ROR1⁺ cells in PBMCs isolated from a healthy donor and a CLL patient (upper panel) and cells isolated from the blood, bone marrow, and spleen (lower panel) of huNSG mice. Samples were pregated as live cells, singlet cells positive for human CD45. The numbers indicate the frequency of CD19⁺ and ROR1⁺ cells within human CD45⁺ cells. (b) Composite data from 3 independent experiments are shown. Each data point represents one individually analyzed mouse. Horizontal lines represent the mean and SD.

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