Liver HLA-E Expression Is Associated with Severity of Liver Disease in Chronic Hepatitis C

Figure 3

Association between HLA-E expression in hepatocyte cytoplasm and liver necroinflammatory activity. HLA-E expression was described in the following grades: 0 (without positive cell expression), 1+ (<25%), 2-3+ (>25 or >50% of positive cell expression). Liver necroinflammatory activity was described according to the METAVIR classification: A0 + 1: no or mild activity, A2: moderate activity, A3: severe activity.