Liver HLA-E Expression Is Associated with Severity of Liver Disease in Chronic Hepatitis C

Figure 4

Association between HLA-E expression in Kupffer cells and liver fibrosis. HLA-E expression was described in the following grades: 0 (without positive cell expression), 1+ (<25%), 2+ (25–50%). There was no grade 3+ expression in this case. Fibrosis was described according to the METAVIR classification: F1: portal fibrosis without septa, F2: portal fibrosis with rare septa, F3-4: numerous septa without and with cirrhosis.