Liver HLA-E Expression Is Associated with Severity of Liver Disease in Chronic Hepatitis C

Table 1

Frequency of HLA-E expression in hepatocyte cytoplasm and Kupffer cell in HCV patients and control subjects.

HLA-E expression in hepatocyte cytoplasm								HLA-E expression in Kupffer cell
	0		1+		2-3+			0		1+		2+
		%		%		%			%		%		%
HCV ()	52	41.6	47	37.6	26	20.8	P	69	55.2	38	30.4	18	14.4	P
Control ()	16	80	04	20	0	0	0.004	18	90	02	10	0	0	0.01

: number of individuals; %: percentage; : value. Grades of HLA-E expression: 0 (without positive cell expression), 1+ (<25%), 2+ (25–50%), and 2-3+ (>25% or >50% of positive cell expression). There was no 3+ HLA-E expression in Kupffer cell.