Immunotherapy with Native Molecule rather than Hypoallergenic Variant of Pru p 3, the Major Peach Allergen, Shows Beneficial Effects in Mice

<div>SCIT with Pru p 3, but not with R/A Pru p 3, increased the number of Th1-type IgG Ab-producing cells in the spleen. After the sensitization with Pru p 3, BALB/c mice received SCIT with 10 or 100 <i>μ</i>g of Pru p 3 or R/A Pru p 3 and challenged with Pru p 3. The numbers of (a) Pru p 3-specific IgE, (b) IgG1, and (c) IgG2a-producing cells in the spleens were measured by ELISPOT.</div>

Journal of Immunology Research

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Figure 4: Immunotherapy with Native Molecule rather than Hypoallergenic Variant of Pru p 3, the Major Peach Allergen, Shows Beneficial Effects in Mice 

Figure 4 | Immunotherapy with Native Molecule rather than Hypoallergenic Variant of Pru p 3, the Major Peach Allergen, Shows Beneficial Effects in Mice 