Total HLA Class I Antigen Loss with the Downregulation of Antigen-Processing Machinery Components in Two Newly Established Sarcomatoid Hepatocellular Carcinoma Cell Lines

Figure 1

In vitro live monolayer cell morphology and growth curves of the four sHCC cell lines. (a) Fibroblastic-like morphology is shown for each of the sHCC cell lines, sHCC29, sHCC63, sHCC74, and SAR-HCV, as they grow as monolayers. (b) Growth curve patterns of the first three sHCC are illustrated. The growth curve of SAR-HCV is not shown as it has been reported previously [23]. The population doubling time and time required for reaching saturation density in culture for each cell line based on the growth curve are listed in the attached table.

(a)

(b)