The Intracellular Growth of M. tuberculosis Is More Associated with High Glucose Levels Than with Impaired Responses of Monocytes from T2D Patients
Table 1
The clinical and demographic characteristics of the T2D patients and healthy subjects.
Healthy ()
T2D ()
Sex (male/female)
9/17
15/28
ns
Age (years)
48 [33-65]
53 [30-68]
ns
Weight (kg)
65 [51-95]
66 [51-114]
ns
Height (m)
1.58 [1.45-1.80]
1.56 [1.44-1.74]
ns
BMI (kg/m2)
26 [23-33]
26 [23-47]
ns
Fasting glucose (mg/dl)
99 [80-115]
210 [106-460]
HbA1c (%)
5.5 [5.0-5.9]
8.9 [6.1-15.6]
()
—
10.3 [9.4-15.6]
Creatinine (mg/dl)
0.77 [0.59-1.10]
0.71 [0.52-1.84]
ns
Cholesterol (mg/dl)
186 [136-313]
200 [147-310]
ns
Triglycerides
132 [70-469]
215 [46-688]
HDL (mg/dl)
39 [26-67]
43.2 [29-70]
ns
LDL (mg/dl)
124 [76-208]
125 [11-228]
ns
Status TST (+/-)
47.8% (11/11)
57.5% (23/17)
ns
T2D = type 2 diabetes mellitus, BMI=body mass index, HbA1c = glycated haemoglobin, HDL = high-density lipid, LDL = low-density lipid, TST = tuberculin skin test, ns = not significant. Values are median [Min–Max]. -test = T2D vs. healthy. Two-sample proportion test for sex and TST.
