Research Article
Functional Polymorphisms and Gene Expression of TLR9 Gene as Protective Factors for Nasopharyngeal Carcinoma Severity and Progression
Table 5
Relative expression of TLR9 mRNA according to NPC clinicopathological parameters at diagnosis.
| | NPC clinicopathological parameters () | Median of TLR9 expression (-03) | valuea |
| | Age | | 0.696 | | (17) | 2.15 | | (33) | 2.24 | | Sex | | 0.419 | | Women (14) | 2.40 | | Men (36) | 2.01 | | Tumor size | | 0.013 | | T1-T2-T3 (36) | 2.52 | | T4 (13) | 1.35 | | Lymph node | | 0.469 | | N0 (5) | 3.13 | | N+ (44) | 2.11 | | Metastasis | | 0.653 | | M0 (42) | 2.20 | | M+ (4) | 1.94 | | Clinical stage | | 0.0374 | | SI-SII (6) | 3.46 | | SIII-SIV (41) | 2.03 |
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a: Mann-Whitney’s test.
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